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Moisturizing Nasal Care
Hydration your nose will love
XyloClean is a naturally-derived xylitol nasal spray that moisturizes dry passages and helps wash away everyday irritants — the refreshing, non-medicated way to stay clear.
- Non-medicated
- No rebound
- Naturally derived
- Daily hydration
- 100%
- Naturally derived
- 0
- Decongestants
- 24/7
- Everyday comfort
Daily hydration
XyloClean Xylitol Nasal Spray
Moisturizing, non-medicated relief for dry noses
- Naturally-derived xylitol humectant
- Rehydrates dry, irritated passages
- No decongestants, no rebound
100%
Naturally-derived xylitol — non-medicated hydration for daily use.
0
No decongestants, no rebound congestion, no drowsiness.
24/7
Comfortable for planes, offices, dry heat, and A/C air.
The Science of Xylitol
How xylitol hydrates
A gentle humectant with real research behind it — here is what xylitol actually does once it reaches your nasal passages.
01
Draws in moisture
Xylitol is a five-carbon sugar alcohol and natural humectant — it attracts and holds water right at the nasal lining where you need it.
02
Supports the airway surface
Research suggests xylitol can lower the salt concentration of the airway surface liquid, which may support the nose's own natural defenses.
03
Helps irritants let go
A hydrated, xylitol-rich surface makes it harder for airborne particles and irritants to cling on, so your nose feels clearer.
04
Gentle, non-medicated
No decongestants and no rebound congestion — just comfortable hydration you can reach for as often as you like.
Naturally derived
Xylitol, the natural humectant
Xylitol is a naturally-derived sugar alcohol found in birch, many fruits, and vegetables — the body even makes small amounts of it. In XyloClean it hydrates the nasal lining and helps keep airborne irritants from clinging on, no medication required.
For dry days
Beat dry, recycled air
Planes, offices, winter heating, and air conditioning all pull moisture from your nose. A few sprays of XyloClean rehydrate parched tissue so you feel clear and comfortable wherever the day takes you.
Everyday gentle
Non-medicated, no rebound
Unlike decongestant sprays, XyloClean is designed for comfortable daily use with no rebound congestion. Cleanse with HypoNasal, then hydrate with XyloClean for a complete routine.
Evidence-informed
Grounded in real research
A natural sugar alcohol
Xylitol occurs naturally in birch bark and many plants, and is widely used as a gentle, low-glycemic humectant across oral and nasal care.
Osmotic hydration
As a humectant, xylitol holds moisture at the mucosal surface, easing the dryness caused by travel, heating, and air conditioning.
Studied in airway research
Xylitol has been investigated in nasal irrigation and airway surface liquid studies for its hydrating and defense-supporting properties.
Selected references
- 1Zabner J, Seiler MP, Launspach JL, et al. The osmolyte xylitol reduces the salt concentration of airway surface liquid and may enhance bacterial killing. Proc Natl Acad Sci USA. 2000;97(21):11614–11619.
- 2Weissman JD, Fernandez F, Hwang PH. Xylitol nasal irrigation in the management of chronic rhinosinusitis. Laryngoscope. 2011;121(11):2468–2472.
- 3Uhari M, Kontiokari T, Niemelä M. A novel use of xylitol sugar in preventing acute otitis media. Pediatrics. 1998;102(4):879–884.
Provided for educational context. XyloClean is a non-medicated moisturizing nasal spray and is not intended to diagnose, treat, cure, or prevent any disease.
Xylitol, explained
Frequently asked questions
What is xylitol and why put it in a nasal spray?
Xylitol is a naturally-derived sugar alcohol and a gentle humectant — it attracts and holds moisture. In a nasal spray it hydrates the nasal lining and helps keep airborne irritants from sticking, all without medication.
Is XyloClean a decongestant?
No. XyloClean is a moisturizing, non-medicated spray. It won't constrict blood vessels and it won't cause the rebound congestion that overusing decongestant sprays can. It simply rehydrates and refreshes.
Can I use XyloClean every day?
Yes — that's exactly what it's made for. Use it whenever your nose feels dry: on flights, in air-conditioned or heated rooms, during allergy season, or as part of your daily routine.
Can I use it together with HypoNasal?
They're designed to work as a pair. Cleanse first with HypoNasal HOCl spray, then hydrate with XyloClean for a complete cleanse-and-moisturize routine.
Is it safe for the whole family?
Cleanse, then hydrate
Pair XyloClean with HypoNasal for a complete daily nasal routine.