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HOCl Nasal Care
Advanced nasal cleansing powered by hypochlorous acid — the gentle, deep-cleaning super-molecule your own immune system already trusts. One family of sprays for every age, from adults to infants.
Deep everyday nasal cleansing for adults
Pure hypochlorous acid concentration — potent, yet remarkably gentle.
Skin- and tissue-friendly, isotonic saline base with no burn.
Free of alcohol, fragrance, and steroids — nothing your nose doesn't need.
THE COMPLETE HOCl FAMILY
HypoNasal, HypoNasal Jr, and HypoBaby all share the same HOCl science — each tuned to the sensitivity of the nose it cares for. Every member of the collection, always in view.
Our flagship spray pairs isotonic saline with hypochlorous acid to wash away dust, pollen, and impurities while soothing sensitive tissue.
The same trusted HOCl science, formulated gentler for growing noses. Rinses away classroom germs and seasonal irritants without the sting.
The Science of HOCl
A closer look at the molecule behind the mist — and why it cleanses so effectively while staying gentle enough for daily use.
When a threat appears, neutrophils — frontline immune cells — generate hypochlorous acid through the enzyme myeloperoxidase as part of the innate immune response.
HOCl is a small, uncharged molecule that disrupts microbial cell walls and proteins on contact, yet is well-tolerated by human tissue at the right concentration and pH.
Nefense holds pharmaceutical-grade HOCl in a pH-balanced, isotonic saline base so its cleansing action stays consistent from the first spray to the last.
A quick mist flushes dust, pollen, and airborne particulates from the nasal lining — no decongestants, no rebound, no drowsiness.
EVIDENCE-INFORMED
Hypochlorous acid isn't foreign to the body — it's produced naturally by white blood cells to help neutralise pathogens, which is part of why it is so well tolerated.
In water, HOCl exists in balance with the hypochlorite ion (OCl⁻). Below roughly pH 6, the active HOCl form dominates — the reason our formula is carefully pH-balanced.
Stabilised HOCl has been researched and used across wound irrigation, dermatology, and eye care for its cleansing properties and gentle tolerability.
Provided for educational context. Nefense products are non-medicated nasal hygiene sprays and are not intended to diagnose, treat, cure, or prevent any disease.
HOCl, explained
Hypochlorous acid is a naturally occurring molecule — the very same one your white blood cells produce to defend against invaders. Nefense stabilises pharmaceutical-grade HOCl in an isotonic saline base so you can put its cleansing power to work every day.
Yes. HypoNasal is non-medicated, steroid-free, and designed for routine daily cleansing. Because it is pH-balanced and isotonic, there is no rebound congestion and no stinging — just a gentle rinse whenever you need it.
Decongestant sprays constrict blood vessels and can cause rebound congestion with overuse. HypoNasal doesn't decongest — it cleanses. It flushes away dust, pollen, and airborne particulates so your nose stays clear the natural way.
Absolutely. The HypoNasal family includes HypoNasal Jr for kids and an ultra-gentle HypoBaby mist for infants, each formulated for the sensitivity of growing noses.
Start with HypoNasal, or add the whole family to your routine.
The mildest mist we make, designed for infants. Clears everyday buildup so tiny noses stay clear and comfortable.
Use it as part of your morning and evening routine, after being outdoors, after travel, or any time your nose feels congested or irritated. There is no daily limit.